发明名称 COMPOSITIONS AND METHODS FOR ARRAY-BASED GENOMIC NUCLEIC ACID ANALYSIS OF BIOLOGICAL MOLECULES
摘要 The invention provides biological molecules modified by reaction with a compound having the formula (I): R1-X-R2, wherein R1 is a cyclic ether group or an amino group, R2 is an alkoxysilane group and X is a moiety chemically suitable for linking the cyclic ether group or the amino group to the alkoxysilane group. The invention also provides arrays, or "biochips", comprising these modified biological molecules. Also provided are methods fo r making and using these compositions.
申请公布号 CA2446050(A1) 申请公布日期 2002.11.21
申请号 CA20012446050 申请日期 2001.05.10
申请人 BAYLOR COLLEGE OF MEDICINE;SPECTRAL GENOMICS, INC. 发明人 BRADLEY, ALLAN;MARATHI, UPENDRA;CAI, WEI WEN
分类号 G01N33/53;C07B61/00;C07H21/00;C07H21/02;C07H21/04;C07K1/107;C07K17/06;C12N15/09;C12Q1/68;C40B60/14;G01N33/547;G01N37/00;(IPC1-7):C07H21/00 主分类号 G01N33/53
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