发明名称 USE OF IL-18 INHIBITORS FOR THE TREATEMENT OR PREVENTION OF SEPSIS
摘要 The present invention relates to the use of an inhibitor of IL.18 in the manufacture of a medicament for the treatment and/or prevention of sepsis and other diseases characteristic to the Systemic Inflammatory Response Syndrome (SIRS) selected from severe sepsis and septic shock, and also for sepsis related cardiac dysfunction.
申请公布号 WO02092008(A2) 申请公布日期 2002.11.21
申请号 WO2002US15556 申请日期 2002.05.16
申请人 YEDA RESEARCH AND DEVELOPMENT CO., LTD.;DINARELLO, CHARLES, A.;FANTUZZI, GIAMILA;KIM, SOO-HYN;REZNIKOV, LEONID;RUBINSTEIN, MEAHEM;NOVICK, DANIELA;SCHWARTSBURD, BORIS 发明人 DINARELLO, CHARLES, A.;FANTUZZI, GIAMILA;KIM, SOO-HYN;REZNIKOV, LEONID;RUBINSTEIN, MEAHEM;NOVICK, DANIELA;SCHWARTSBURD, BORIS
分类号 A61K45/00;A61K31/7088;A61K38/00;A61K38/17;A61K38/21;A61K38/55;A61K39/395;A61K47/48;A61K48/00;A61P7/00;A61P9/04;A61P29/00;A61P31/04;A61P43/00;C07K16/24;C07K16/28 主分类号 A61K45/00
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