发明名称 |
Naphthyl-Derivate, Zwischenprodukte, Verfahren, Zusammensetzungen, die sie enthalten |
摘要 |
<p>The present invention provides a compound of formula I <CHEM> wherein R<1> is -H, -OH, -O(C1-C4 alkyl), -OCOC6H5, -OCO(C1-C6 alkyl), or -OSO2(C4-C6 alkyl); R<2> is -H, -OH, -O(C1-C4 alkyl), -OCOC6H5, -OCO(C1-C6 alkyl) or -OSO2(C4-C6 alkyl); n is 2 or 3; and R<3> is 1-piperidinyl, 1-pyrrolidinyl, methyl-1-pyrrolidinyl, dimethyl-1-pyrrolidinyl, 4-morpholino, dimethylamino, diethylamino, or 1-hexamethyleneimino; or a pharmaceutically acceptable salt thereof. The compounds are useful for treating diseases such as post-menopausal syndrome, and uterine fibroid disease, endometriosis, and aortal smooth muscle cell proliferation.</p> |
申请公布号 |
DE69525699(T2) |
申请公布日期 |
2002.11.21 |
申请号 |
DE1995625699T |
申请日期 |
1995.09.18 |
申请人 |
ELI LILLY AND CO., INDIANAPOLIS |
发明人 |
BRYANT, HENRY UHLMANN;CULLINAN, GEORGE JOSEPH;DODGE, JEFFREY ALAN;FAHEY, KENNAN JOSEPH;JONES, CHARLES DAVID;LUGAR III, CHARLES WILLIS;MUEHL, BRIAN STEPHEN |
分类号 |
C07D295/08;A61K31/13;A61K31/135;A61K31/40;A61K31/445;A61K31/4453;A61K31/535;A61K31/5375;A61K31/55;A61P3/02;A61P3/06;A61P13/02;A61P15/00;A61P15/12;A61P19/10;A61P35/00;A61P43/00;C07C211/19;C07C213/08;C07C217/18;C07C303/26;C07C309/65;C07D207/06;C07D207/08;C07D211/22;C07D295/088;C07D295/092;(IPC1-7):C07D295/08 |
主分类号 |
C07D295/08 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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