发明名称 NOVEL USE OF 2H-BENZIMIDAZOL-2-ONE, 1,3-DIHADRO-1-(2{4-{3-(TRIFLUOROMETHYL}PHENYL]-1-PIPERAZINYL}ETHYL)- AND ITS PHYSIOLOGICALLY ACCEPTABLE ACID ADDITION SALTS
摘要 Use of 2H-benzimidazol-2-one, 1,3-dihydro-1-(2{4-[-(trifluoromethyl)phenyl]- 1- piperazinyl}ethyl)-or a physiologically acceptable acid addition salt thereo f, for the manufacture of a medicament for the treatment of extrapyramidal movement disorders. These extrapyramidal movement disorders may result from idopathic Parkinson's disease, from the adverse effects of the administratio n of anti-Parkinson drugs in idiopathic Parkinson's disease, from dyskinesias caused by idiopathic Parkinson's disease and/or long-term administration of anti-Parkinson drugs, from Parkinson-like or Parkinson-related syndromes of from Parkinsonoid symptomes. Another aspect of the present invention concern s a pharmaceutical composition comprising, as active ingredients -(I) 2H- benzimidazol-2-one, 1,3-dihydro-1-(2-{4-[3-(trifluoromethyl)phenyl]-1- piperazinyl}ethyl)-or a physiologically acceptable acid addition salt thereo f, and (II) at least one anti-Parkinson drug, in combination with one or more pharmaceutically acceptable excipients.
申请公布号 CA2444062(A1) 申请公布日期 2002.11.21
申请号 CA20022444062 申请日期 2002.05.10
申请人 BECK, JURGEN K. 发明人 BECK, JURGEN K.
分类号 C07D235/26;A61K31/165;A61K31/198;A61K31/495;A61K31/496;A61P25/02;A61P25/14;A61P25/16;(IPC1-7):A61K31/495 主分类号 C07D235/26
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