| 发明名称 |
ANTISENSE MODULATION OF PTP1B EXPRESSION |
| 摘要 |
<p>Compounds, compositions and methods are provided for modulating the expressi on of PTP1B. The compositions comprise antisense compounds, particularly antisense oligonucleotides, targeted to nucleic acids encoding PTP1B. Method s of using these compounds for modulation of PTP1B expression and for treatmen t of diseases associated with expression of PTP1B are provided.</p> |
| 申请公布号 |
CA2447004(A1) |
申请公布日期 |
2002.11.21 |
| 申请号 |
CA20022447004 |
申请日期 |
2002.05.13 |
| 申请人 |
ISIS PHARMACEUTICALS, INC. |
发明人 |
FREIER, SUSAN M.;MONIA, BRETT P.;BUTLER, MADELINE M.;MCKAY, ROBERT;WYATT, JACQUELINE;COWSERT, LEX M. |
| 分类号 |
C12N15/09;A61K31/7115;A61K31/712;A61K31/7125;A61K38/00;A61K48/00;A61P3/04;A61P3/10;A61P35/00;C12N15/113;(IPC1-7):C12Q1/68;C07H21/00;C07H21/02;A01N43/04;C12P19/34;C12N15/63;C07H21/04 |
主分类号 |
C12N15/09 |
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