发明名称 |
Lipophilic peptides for macromolecule delivery |
摘要 |
Peptide-macromolecule complexes for delivery of nucleic acid to a cell. The nucleic acid carrier includes a binding complex. The binding complex contains a binding moiety which noncovalently binds to the nucleic acid. The binding complex can also contain a binding moiety which is associated with a surface ligand, nuclear ligand or a lysis agent. These may be associated with the binding moiety by spacers. In addition, the carrier may include a nucleic acid with a combination of the above binding complexes or binding moieties.
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申请公布号 |
US2002173456(A1) |
申请公布日期 |
2002.11.21 |
申请号 |
US20010805301 |
申请日期 |
2001.03.12 |
申请人 |
BAYLOR COLLEGE OF MEDICINE |
发明人 |
SMITH LOUIS C.;SOARROW JAMES T.;HAUER JOCHEN;MIMS MARTHA P. |
分类号 |
A61K38/00;A61K47/48;C07K7/06;C07K7/08;(IPC1-7):A61K38/16;C07K14/435 |
主分类号 |
A61K38/00 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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