发明名称 |
NOVEL 5-PHENYL-1H-INDOLE DERIVATIVES AS ANTAGONISTS OF INTERLEUKINE-8 RECEPTORS |
摘要 |
The invention concerns 5-phenyl-<i>1H</i>-indole derivatives of formula (I), wherein: R>1<, R>2<, R>3< and R>4< are such as defined in Claim 1, as well as their pharmaceutically acceptable salts, solvates and hydrates. The invention also concerns pharmaceutical compositions containing them, and their use for preparing medicines mediated by the activation of the CXCR receptor of interleukine-8 and chemokines of the same family.
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申请公布号 |
WO02092567(A1) |
申请公布日期 |
2002.11.21 |
申请号 |
WO2002FR01649 |
申请日期 |
2002.05.16 |
申请人 |
LABORATOIRES FOURNIER SA;BARTH, MARTINE;DODEY, PIERRE;PAQUET, JEAN-LUC |
发明人 |
BARTH, MARTINE;DODEY, PIERRE;PAQUET, JEAN-LUC |
分类号 |
A61K31/405;A61K31/4192;A61P1/00;A61P1/02;A61P7/00;A61P7/02;A61P9/06;A61P9/10;A61P11/00;A61P11/06;A61P13/12;A61P17/02;A61P17/06;A61P19/02;A61P19/10;A61P25/00;A61P25/28;A61P29/00;A61P31/12;A61P37/02;A61P43/00;C07D209/18;C07D403/04;(IPC1-7):C07D209/18 |
主分类号 |
A61K31/405 |
代理机构 |
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代理人 |
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地址 |
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