发明名称 NOVEL 5-PHENYL-1H-INDOLE DERIVATIVES AS ANTAGONISTS OF INTERLEUKINE-8 RECEPTORS
摘要 The invention concerns 5-phenyl-<i>1H</i>-indole derivatives of formula (I), wherein: R>1<, R>2<, R>3< and R>4< are such as defined in Claim 1, as well as their pharmaceutically acceptable salts, solvates and hydrates. The invention also concerns pharmaceutical compositions containing them, and their use for preparing medicines mediated by the activation of the CXCR receptor of interleukine-8 and chemokines of the same family.
申请公布号 WO02092567(A1) 申请公布日期 2002.11.21
申请号 WO2002FR01649 申请日期 2002.05.16
申请人 LABORATOIRES FOURNIER SA;BARTH, MARTINE;DODEY, PIERRE;PAQUET, JEAN-LUC 发明人 BARTH, MARTINE;DODEY, PIERRE;PAQUET, JEAN-LUC
分类号 A61K31/405;A61K31/4192;A61P1/00;A61P1/02;A61P7/00;A61P7/02;A61P9/06;A61P9/10;A61P11/00;A61P11/06;A61P13/12;A61P17/02;A61P17/06;A61P19/02;A61P19/10;A61P25/00;A61P25/28;A61P29/00;A61P31/12;A61P37/02;A61P43/00;C07D209/18;C07D403/04;(IPC1-7):C07D209/18 主分类号 A61K31/405
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