发明名称 |
Vascular embolizing agent |
摘要 |
<p>A method for vascular embolization of a blood vessel of a patient comprises introducing a novel vascular embolizing agent which is an aqueous solution of a specific thermosensitive polymer, which is liquid at low temperatures but causes coagulation when heated to the body temperature of the patient, into the blood vessel followed by in situ heating of the solution. The thermosensitive polymer found to be suitable for the purpose is a homopolymer or copolymer of an N-substituted (meth)acrylamide monomer having a specified intrinsic viscosity in tetrahydrofuran and gives an aqueous solution capable of exhibiting phase transition from a liquid to a coagulate at a transition temperature of 10 to 37 DEG C.</p> |
申请公布号 |
EP0704217(B1) |
申请公布日期 |
2002.11.20 |
申请号 |
EP19950301729 |
申请日期 |
1995.03.15 |
申请人 |
NATIONAL INSTITUTE OF ADVANCED INDUSTRIAL SCIENCE AND TECHNOLOGY |
发明人 |
ITO, SHOJI;MATSUMARU, YUJI;HIRANO, TAKASHI;OHASHI, SHINICHI |
分类号 |
A61K31/785;A61K49/00;A61P9/00;(IPC1-7):A61K31/785;A61P7/00 |
主分类号 |
A61K31/785 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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