1-trifluoromethyl-4-hydroxy-7-piperidinyl-aminomethyl-chroman derivatives.

摘要

This invention relates to novel 1-trifluoromethyl-4-hydroxy-7-piperidinylaminomethylchroman derivatives of the formulawherein R1 is C1-C6 alkyl;R2 is hydrogen, C1-C6 alkyl, halo C1-C6 alkyl or phenyl;R3 is hydrogen or halo; andR4 and R5 are independently hydrogen, C1-C6 alkyl or halo C1-C6 alkyl,their pharmaceutically acceptable salts, pharmaceutical compositions containing such compounds, and the use of such compounds to treat CNS, gastrointestinal and other disorders.