发明名称 |
Use of neomycin for treating angiogenesis-related diseases |
摘要 |
The present invention is directed to using neomycin or an analogue thereof as an therapeutic agent to treat angiogenesis-related diseases, which are characterized by excessive, undesired or inappropriate angiogenesis or proliferation of endothelial cells. The present invention is also directed to pharmaceutical compositions comprising (a) neomycin or an analogue and, optionally, (b) another anti-angiogenic agent or an anti-neoplastic agent. The present invention is further directed to a method for screening neomycin analogues having anti-angiogenic activity. A preferred embodiment of the invention relates to using neomycin to treat subjects having such diseases.
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申请公布号 |
US6482802(B1) |
申请公布日期 |
2002.11.19 |
申请号 |
US20000700436 |
申请日期 |
2000.11.09 |
申请人 |
ENDOWMENT FOR RESEARCH IN HUMAN BIOLOGY, INC. |
发明人 |
HU GUO-FU;VALLEE BERT L. |
分类号 |
A61K31/436;A61K31/7036;A61K38/04;A61K38/08;A61K38/16;A61K38/18;A61K38/21;A61K45/06;G01N33/50;G01N33/68;G01N33/74;(IPC1-7):A61K31/37 |
主分类号 |
A61K31/436 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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