| 发明名称 |
PYRANYLPHENYL HYDROXYALKYLNAPHTHOIC ACIDS AS INHIBITORS OF LEUKOTRIENE BIOSYNTHESIS |
| 摘要 |
Compounds having the formula I: (see formula I) are inhibitors of leukotriene biosynthesis. These compounds are useful as anti-asthmatic, anti-allergic, anti-inflammatory, and cytoprotective agents. They are also useful in treating angina, cerebral spasm, glomerular nephritis, hepatitis, endotoxemia, uveitis and allograft rejection and in preventing the formation of atherosclerotic plaques.
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| 申请公布号 |
CA2061706(C) |
申请公布日期 |
2002.11.19 |
| 申请号 |
CA19922061706 |
申请日期 |
1992.02.24 |
| 申请人 |
MERCK FROSST CANADA & CO. |
发明人 |
YOUNG, ROBERT N.;GILLARD, JOHN W.;GIRARD, YVES;TRIMBLE, LAIRD A.;SCHEIGETZ, JOHN;DUCHARME, YVES;YERGEY, JAMES A.;NICOLL-GRIFFITH, DEBORAH;HUTCHINSON, JOHN H. |
| 分类号 |
A61K31/35;A61K31/351;A61K31/352;A61K31/38;A61K31/382;A61K31/535;A61K31/5375;A61P1/16;A61P9/00;A61P9/10;A61P11/00;A61P13/02;A61P15/00;A61P27/02;A61P27/14;A61P29/00;A61P37/06;A61P37/08;A61P43/00;C07C63/36;C07C65/11;C07C65/24;C07D295/08;C07D295/096;C07D295/24;C07D309/06;C07D309/10;C07D309/12;C07D309/30;C07D311/92;C07D335/02;C07D493/08;(IPC1-7):C07D309/10;C07D491/08;C07D295/155;C07C65/17;A61K31/19;C07D265/30 |
主分类号 |
A61K31/35 |
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