发明名称 Therapeutically usable synthetic oligonucleotides
摘要 <p>The present invention provides a composition comprising an isolated 3'-OH, 5'-OH synthetic phosphodiester nucleotide sequence selected from the group consisting of SEQ ID Nos: 7-18, 23-44, 46, 47, 50-66 and 81-83 and further comprising a pharmaceutically acceptable carrier and wherein the sequence induces a response selected from the group consisting of induction of cell cycle arrest, inhibition of proliferation, activation of caspases and induction of apoptosis in cancer cells and production of cytokines by immune system cells.</p>
申请公布号 CZ20022372(A3) 申请公布日期 2002.11.13
申请号 CZ20020002372 申请日期 2000.12.12
申请人 BIONICHE LIFE SCIENCES INC. 发明人 PHILLIPS NIGEL C.;FILION MARIO C.
分类号 A61K48/00;A61K31/00;A61K31/138;A61K31/513;A61K31/7084;A61K31/7088;A61K31/7125;A61K38/00;A61K45/00;A61K45/06;A61P7/00;A61P29/00;A61P31/00;A61P35/00;A61P35/02;A61P35/04;A61P37/02;A61P37/04;A61P43/00;C12N15/117;(IPC1-7):C12N15/11;A61K31/708 主分类号 A61K48/00
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