发明名称 |
DIOXIN DERIVATIVES AND METHOD OF MEASUREMENT THEREWITH |
摘要 |
<p>The invention provides a highly sensitive measurement and detection technique for dioxins, which has advantages inherent to immunoassay; and markers to be used in the technique. Disclosed are a biotinylated dioxin derivative of formula (1): <CHEM> (wherein X represents a hydrogen atom or a chlorine atom; R<1> represents a biotin residue; R<2>'s, which may be identical to or different from one another, independently and individually represent an arginine residue or a lysine residue; n is an integer from 1 to 5 inclusive; and m is an integer from 1 to 3 inclusive), and an immunoassay method for dioxins characterized by using the derivatives as a marker.</p> |
申请公布号 |
EP1256579(A1) |
申请公布日期 |
2002.11.13 |
申请号 |
EP20010904503 |
申请日期 |
2001.02.16 |
申请人 |
OTSUKA PHARMACEUTICAL CO., LTD. |
发明人 |
YANAIHARA, NOBORU;KODAIRA, TSUKASA |
分类号 |
C07D319/24;G01N33/53;G01N33/531;(IPC1-7):C07D319/24 |
主分类号 |
C07D319/24 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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