发明名称 PREVENTIVE OR THERAPEUTIC AGENTS FOR GASTRIC OR ESOPHAGEAL REGURGITATION
摘要 <p>The compound of the following formula: &lt;Chemistry id="chema01" num="0001"&gt;&lt;Image id="ia01" he="35" wi="65" file="IMGA0001.TIF" imgContent="chem" imgFormat="TIFF" /&gt;&lt;/Chemistry&gt; wherein R&lt;Sup&gt;1&lt;/Sup&gt; and R&lt;Sup&gt;2&lt;/Sup&gt; independently represent a hydrogen atom or a lower alkyl group; A represents a group selected from the group consisting of 1-azabicyclo[3.2.2]nonyl group, 1-azabicyclo[2.2.2]octyl group, or an N-oxide thereof, or a pharmaceutically acceptable salt thereof or a hydrate thereof has both improving effect on enterokinetic functions and suppressing effect on acid secretion, and also is highly safe. Accordingly, the substance is useful as preventive or therapeutic medicament for a gastroesophageal reflux disease.</p>
申请公布号 EP1256581(A1) 申请公布日期 2002.11.13
申请号 EP20010902793 申请日期 2001.02.07
申请人 MITSUBISHI PHARMA CORPORATION 发明人 YAMAZAKI, SATOSHI
分类号 A61K31/439;A61P1/04;C07D495/04;C07D519/00;(IPC1-7):C07D453/02;A61K31/55 主分类号 A61K31/439
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