<p>The present invention relates to a method for preparing adefovir dipivoxil comprising contacting 9-Ä2-(phosphonomethoxy)ethylÜadenine with chloromethyl pivalate in 1-methyl-2-pyrrolidinone and a trialkylamine and recovering adefovir dipivoxil.</p>
申请公布号
EP1256584(A1)
申请公布日期
2002.11.13
申请号
EP20020016428
申请日期
1998.07.23
申请人
GILEAD SCIENCES, INC.
发明人
ARIMILLI, MURTY N;LEE, THOMAS T.K;MANES, LAWRENCE V;MUNGER, JOHN D.,JR.;PRISBE, ERNEST J;SCHULTZE, LISA, M;KELLY, DAPHNE E
