发明名称 METHOD FOR DETECTING UNKNOWN OR KNOWN NUCLEIC ACID MUTATION USING NUCLEIC ACID MELT CURVE AND NUCLEIC ACID DISSOCIATION CURVE, AND EXHIBITION METHOD THEREOF
摘要 PROBLEM TO BE SOLVED: To provide a method for detecting an unknown and known nucleic acid mutation rapidly, easily and at a low cost, and an exhibition method thereof. SOLUTION: Problems are solved by a method for detecting a nucleic acid mutation through a difference and a feature of a temperature (Tm value) in which a double-stranded nucleic acid or an amplification product thereof is heated to melt into a single-stranded nucleic acid. The unknown and known nucleic acid mutation can be detected rapidly, easily and at a low cost by comparing and collating a Tm value, a Tm pattern and a change thereof of a sample with an obtained existing Tm value, a Tm pattern and a change thereof accumulated as a data base.
申请公布号 JP2002325581(A) 申请公布日期 2002.11.12
申请号 JP20010168840 申请日期 2001.04.27
申请人 ADGENE CO LTD 发明人 OSHIMA JOJI
分类号 C12N15/09;C12Q1/68 主分类号 C12N15/09
代理机构 代理人
主权项
地址