2'-O,4'-CROSSLINKED NUCLEOSIDE TRIPHOSPHATE

摘要

PROBLEM TO BE SOLVED: To provide a substrate possible to amplify a gene simply and accurately in a gene amplification using RNA polymerase. SOLUTION: The compound represented by general formula (1): (wherein A is a 1-4C alkylene group, B is purin-9-yl group, 2-oxo-1,2-dihydropyrimidin-1-yl group or substituted purin-9-yl group or substituted 2-oxo-1,2-dihydropyrimidin-1- yl group, and X is oxygen atom or sulfur atom) and its salt are provided.