发明名称 HU ANTIGEN-DERIVED PEPTIDES AND USES THEREOF
摘要 The present invention relates to Hu antigen-derived peptides and to their us e, and more particularly to their use in the diagnostic, in the prevention and in the treatment of certain types of cancer and neuronal damage. The immunogenic peptides of the invention are capable of generating cytotoxic CD8 T- lymphocytes (CTLs) which may eliminate undesirable cells such as SCLC cancerous cell, without reacting against non-cancerous such as neural cells. The invention also provides nucleotides coding these immunogenic peptides and antibodies bindin g thereto.
申请公布号 CA2387391(A1) 申请公布日期 2002.11.08
申请号 CA20022387391 申请日期 2002.05.08
申请人 INSERM;INSTITUT PASTEUR;ASSISTANCE PUBLIQUE HOPITAUX DE PARIS 发明人 FARCET, JEAN-PIERRE;GARCIA-PONS, FRANCISCO;LANGLADE-DEMOYEN, PIERRE;BOURGUIN-PLONQUET, ANNE;GHERARDI, ROMAIN K.
分类号 A61K39/00;C07K14/47;G01N33/574;(IPC1-7):C12N15/12;C07K14/00;C07K16/00;C12N5/00;A61P35/00;A61K38/16;A61K39/395;C07K14/52;C12N15/63;A61K31/708 主分类号 A61K39/00
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