摘要 |
PROBLEM TO BE SOLVED: To provide a low molecular peptide having an activity of potato carboxypeptidase inhibitor(PCI), an inhibitor of carboxypeptidase R(CPR). SOLUTION: The low molecular peptide having the following amino acid sequence; (a) Cys-Lys-Pro-Ala-Lys-Asn-Ala-Arg-Cys, or (b) an amino acid sequence wherein one or more amino acids in the amino acid sequence (a) are deleted, substituted or added, or an amino acid sequence containing an amino acid chemically modified by monoiodoacetic acid and the like, and inhibiting carboxypeptidase R activity, and the pharmaceutical composition containing the same are provided.
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