FUSED BICYCLIC AMINES

摘要

Compounds of formula (1) are described wherein Ar is an optionally substituted aryl, heteroaryl, aralkyl, heteroaralkyl or alkyl group, X is a nitrogen atom or a C(R<1a>) group, n is zero or the integer 1 or 2 and R, R<1>, R<2>, R<3> and R<4> are substituents defined in the specification. The compounds are able to inhibit the activity of Class 1 receptor tyrosine kinases and are of use in the treatment of hyperproliferative disorders such as psoriasis.