发明名称 6H-OXAZOLO[4,5-E]INDOLE DERIVATIVES AS NICOTINIC ACETYLCHOLINE RECEPTOR LIGANDS AND/OR SEROTONERGIC LIGANDS
摘要 Compounds of the formula I in which R1, R2, R3 and R4 are as defined in Clai m 1, are ligands of the nicotinic acetylcholine receptor and/or serotonergic ligands and are suitable for the prophylaxis or treatment of psychoses, schizophrenia, depression, anxiety states, dementia, in particular Alzheimer 's disease and Lewy bodies dementia, neurodegenerative disorders, Parkinson's disease, amyotrophic lateral sclerosis, Huntington's disease, Tourette's syndrome, learning and memory restrictions, bulimia anorexia nervosa or othe r eating disorders, compulsvie behaviour, premenstrual syndrome, age-induced memory impairment, amelioration of withdrawal symptoms in nicotine dependenc e, strokes or brain damage by toxic compounds, and for the treatment of disorde rs which are characterised by an excess of circulating serotonin or by serotonergic hyperactivity.
申请公布号 CA2445835(A1) 申请公布日期 2002.11.07
申请号 CA20022445835 申请日期 2002.04.05
申请人 MERCK PATENT GESELLSCHAFT MIT BESCHRAENKTER HAFTUNG 发明人 SCHIEMANN, KAI;LEIBROCK, JOACHIM;BOETTCHER, HENNING
分类号 A61K31/439;A61K31/454;A61K31/496;A61P1/14;A61P3/04;A61P5/24;A61P15/00;A61P21/00;A61P25/00;A61P25/14;A61P25/16;A61P25/18;A61P25/22;A61P25/24;A61P25/28;A61P25/34;A61P43/00;C07D498/04;C07D519/00;(IPC1-7):C07D498/04;A61K31/42;A61K31/435 主分类号 A61K31/439
代理机构 代理人
主权项
地址