USE OF AGT AND ITS DERIVATIVES FOR MANUFACTURING ANTI-ANGIOGENESIS PHARMACEUTICAL COMPOSITIONS

摘要

An object of the present invention is the use of at least one inhibitor of angiogenesis consisting of AGT or derivatives thereof in the manufacture of a drug for treating pathologies or disorders notably angiogenesis-dependent or mediated pathologies generally characterised by excessive angiogenesis.The present invention also relates to a cell transfected with at least one expression vector wherein said expression vector hosts a recombinant nucleic acid encoding an AGT or one of its derivatives for use in therapy of angiogenesis-mediated pathologies. The present invention further relates to an expression vector for use in said cell.