TWO-PHASE, WATER-ABSORBENT BIOADHESIVE COMPOSITION

摘要

An adhesive composition is provided that contains both a hydrophobic phase a nd a hydrophilic phase, wherin the hydrophobic phase is composed of a crosslink ed hydrophobic polymer composition and the hydrophilic phase is a water-absorbe nt blend of a hydrophilic polymer and a complementary oligomer capable of crosslinking the hydrophilic polymer through hydrogen bonding, ionic bonding , and/or covalent bonding. The composition is useful as a bioadhesive, for affixing drug delivery systems, wound dressings, bandages, cushions, or the like to a body surface such as skin or mucosal tissue.