| 发明名称 |
Subtle mitochondrial mutations as tumor markers |
| 摘要 |
The accumulation of homoplasmic somatic mutations has been observed in the mitochondrial DNA of certain tumor cells. The presence or recurrence of a tumor can be detected by determining the presence of single basepair mutations in the mitochondrial genome from a cell sample of a patient.
|
| 申请公布号 |
US2002164622(A1) |
申请公布日期 |
2002.11.07 |
| 申请号 |
US20020053611 |
申请日期 |
2002.01.24 |
| 申请人 |
THE JOHNS HOPKINS UNIVERSITY |
发明人 |
POLYAK KORNELIA;VOGELSTEIN BERT;KINZLER KENNETH W. |
| 分类号 |
G01N33/53;C12N5/08;C12N15/09;C12Q1/68;G01N33/566;(IPC1-7):C12Q1/68 |
主分类号 |
G01N33/53 |
| 代理机构 |
|
代理人 |
|
| 主权项 |
|
| 地址 |
|
