发明名称 PKB-3564 SUBSTANCE WITH NEOVASCULARIZATION INHIBITORY ACTIVITY
摘要 A compound represented by the formula (I): (I) wherein R<1> represents hydrogen and R<2> represents hydroxy, provided that R<1> and R<2> in combination may represent oxo or an oxime group; R<3> represents hydrogen and R<4> represents hydroxy, provided that R<3> and R<4> in combination may represent oxo or an oxime group; R<5> represents hydrogen and R<6> represents hydroxy, provided that R<5> and R<6> in combination may represent oxo or an oxime group; R<7> represents hydrogen and R<8> represents hydrogen, provided that R<7> and R<8> in combination may represent oxo or an oxime group; and R<9> and R<10> each represents hydrogen, alkyl, or alkenyl. It is useful as an active ingredient for medicines which have neovascularization inhibitory activity, apotosis inhibitory activity, and cell cycle inhibitory activity.
申请公布号 WO02088137(A1) 申请公布日期 2002.11.07
申请号 WO2002JP04086 申请日期 2002.04.24
申请人 RIKEN;INSTITUTE OF BIOTECHNOLOGY APPLIED TO SOIL EUMYCETES;OSADA, HIROYUKI;KAKEYA, HIDEAKI;KONNO, HIROSHI;KANAZAWA, SUSUMU 发明人 OSADA, HIROYUKI;KAKEYA, HIDEAKI;KONNO, HIROSHI;KANAZAWA, SUSUMU
分类号 A61K31/352;A61P1/04;A61P1/16;A61P3/10;A61P9/04;A61P9/10;A61P13/12;A61P17/14;A61P19/02;A61P25/16;A61P25/28;A61P29/00;A61P31/20;A61P35/00;A61P37/02;A61P43/00;C07D493/22;(IPC1-7):C07D493/22 主分类号 A61K31/352
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