发明名称 |
PKB-3564 SUBSTANCE WITH NEOVASCULARIZATION INHIBITORY ACTIVITY |
摘要 |
A compound represented by the formula (I): (I) wherein R<1> represents hydrogen and R<2> represents hydroxy, provided that R<1> and R<2> in combination may represent oxo or an oxime group; R<3> represents hydrogen and R<4> represents hydroxy, provided that R<3> and R<4> in combination may represent oxo or an oxime group; R<5> represents hydrogen and R<6> represents hydroxy, provided that R<5> and R<6> in combination may represent oxo or an oxime group; R<7> represents hydrogen and R<8> represents hydrogen, provided that R<7> and R<8> in combination may represent oxo or an oxime group; and R<9> and R<10> each represents hydrogen, alkyl, or alkenyl. It is useful as an active ingredient for medicines which have neovascularization inhibitory activity, apotosis inhibitory activity, and cell cycle inhibitory activity.
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申请公布号 |
WO02088137(A1) |
申请公布日期 |
2002.11.07 |
申请号 |
WO2002JP04086 |
申请日期 |
2002.04.24 |
申请人 |
RIKEN;INSTITUTE OF BIOTECHNOLOGY APPLIED TO SOIL EUMYCETES;OSADA, HIROYUKI;KAKEYA, HIDEAKI;KONNO, HIROSHI;KANAZAWA, SUSUMU |
发明人 |
OSADA, HIROYUKI;KAKEYA, HIDEAKI;KONNO, HIROSHI;KANAZAWA, SUSUMU |
分类号 |
A61K31/352;A61P1/04;A61P1/16;A61P3/10;A61P9/04;A61P9/10;A61P13/12;A61P17/14;A61P19/02;A61P25/16;A61P25/28;A61P29/00;A61P31/20;A61P35/00;A61P37/02;A61P43/00;C07D493/22;(IPC1-7):C07D493/22 |
主分类号 |
A61K31/352 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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