发明名称 |
Methods and compositions for delivery and retention of active agents to lymph nodes |
摘要 |
The present invention is directed to delivery and retention of active agents to targeted lymph nodes in a mammal using a ligand/anti-ligand pair. More particularly, the invention involves methods, compositions, and kits for delivery and retention of active agents to targeted lymph nodes using compositions comprising a ligand-colloid moiety and compositions comprising an anti-ligand. Active agents may be associated with one or more of the colloid, ligand, or anti-ligand. Conjugation of the ligand and anti-ligand after administration permits retention of aggregated colloid complex in targeted lymph nodes.
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申请公布号 |
US2002164648(A1) |
申请公布日期 |
2002.11.07 |
申请号 |
US20020044650 |
申请日期 |
2002.01.11 |
申请人 |
BOARD OF REGENTS, THE UNIVERSITY OF TEXAS SYSTEM |
发明人 |
GOINS BETH A.;PHILLIPS WILLIAM T. |
分类号 |
A61K47/48;A61K51/12;(IPC1-7):G01N33/53 |
主分类号 |
A61K47/48 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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