| 摘要 |
<p>Inhibitors capable of enhancing the reaction accuracy in hybridization by inhibiting nonspecific hybridization; clinical examination reagents; and a clinical examination method whereby nonspecific hybridization can be inhibited and a nucleic acid-relating substance to be assayed can be easily and highly accurately detected in a clinical examination. These inhibitors and clinical examination reagents contain a polymer (H) having at least one of carboxyl and sulfone groups and a phosphorylcholine-like group in its molecule, have a weight-average molecular weight of 1000 to 5000000 and exhibit an effect of inhibiting nonspecific hybridization. The above clinical examination method involves the step of bringing a specimen into contact with an examination reagent hybridizable with a definite nucleic acid-relating substance in the presence of the above inhibitor.</p> |
