发明名称 SUBSTITUTED INDOLINONES AS TYROSINE KINASE INHIBITORS.
摘要 <p>The invention relates to substituted indolinones of the general formula (I), in which R1 to R6 and X are defined as per claim 1, to their isomers and salts, in particular, their physiologically compatible salts which exhibit valuable pharmacological properties, in particular an inhibiting effect on various receptor tyrosine kinases, cyclinCDK complexes and also on the proliferation of endothelial cells and different tumour cells. The invention also relates to medicaments containing these compounds, to their use and to a method for their production.</p>
申请公布号 MXPA02002097(A) 申请公布日期 2002.11.07
申请号 MX2002PA02097 申请日期 2000.08.22
申请人 BOEHRINGER INGELHEIM PHARMA KG. 发明人 ARMIN HECKEL
分类号 A61K31/404;A61K31/41;A61K31/4178;A61K31/454;A61K31/496;A61P35/00;A61P43/00;C07D209/34;C07D401/04;C07D401/12;C07D401/14;C07D403/04;C07D403/12;C07D491/04 主分类号 A61K31/404
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