发明名称 NITROGEN-CONTAINING 5-MEMBERED CYCLIC COMPOUNDS AND DRUGS CONTAINING THESE COMPOUNDS AS THE ACTIVE INGREDIENT
摘要 <p>An N-containing five-membered ring compound of formula (I) &lt;CHEM&gt; wherein all symbols are the same as described in the specification, and a non-toxic salt thereof. The compound of formula (I) has an inhibitory activity against cysteine protease and therefore it is useful as an agent for the prophylaxis and/or treatment of inflammatory diseases, diseases induced by apoptosis, diseases induced by disorders of immune responses, autoimmune diseases, diseases induced by decomposition of proteins which compose organism, shock, circulatory system disorders, blood coagulation systems disorders, malignant tumors, acquired immune deficiency syndrome (AIDS) and AIDS-related complex (ARC), parasitic diseases, nerve degeneration diseases, pulmonary disorders, bone resorption diseases, endocrinesthenia, etc.</p>
申请公布号 EP1254901(A1) 申请公布日期 2002.11.06
申请号 EP20010946857 申请日期 2001.01.25
申请人 ONO PHARMACEUTICAL CO., LTD. 发明人 OHMOTO, KAZUYUKI;ITAGAKI, IORI
分类号 A61K31/454;A61K31/5377;C07D257/04;C07D257/06;C07D271/06;C07D271/07;C07D401/04;C07D401/06;C07D403/12;C07D413/04;C07D413/06;A61K31/41;A61K31/4245;A61K31/4439;(IPC1-7):C07D271/06 主分类号 A61K31/454
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