N-substituted-aminomethyl cyclopropyl ketone derivatives or salts thereof and production process therefor

摘要

Novel N-substituted-aminomethyl cyclopropyl ketone derivatives are represented by following Formula (1) :
<Chemistry id="chema01" num="0001"><Image id="ia01" he="22" wi="69" file="IMGA0001.TIF" imgContent="chem" imgFormat="TIFF" /></Chemistry> wherein R<Sup>1</Sup>, R<Sup>2</Sup> and R<Sup>3</Sup> are each a hydrogen atom or an aliphatic hydrocarbon group; and R<Sup>4</Sup> and R<Sup>5</Sup> are each a hydrogen atom or an arylmethyl group which may have a substituent, where at least one hydrogen atom or aryl group as a substituent is combined with a carbon atom in the methyl moiety of the arylmethyl group, and at least one of R<Sup>4</Sup> and R<Sup>5</Sup> is an arylmethyl group which may have a substituent. These compounds are useful for the preparation of aminomethyl cyclopropyl ketone derivatives and 2-amino-1-cyclopropylethanol derivatives or salts thereof.