| 摘要 |
A method of treatment of the human or non-human animal body for treating NO- dependent microcirculation disorders is disclosed, for example microcirculation disorders caused by metabolic diseases, such as elevated levels of homocystin-homocystein inflammatory reactions or autoimmune diseases, furthermore peripheral microcirculation disorders or microcirculation disorders associated with increased cell fragmentation, whi ch method comprises administering to a human or non-human animal body in need o f such treatment an effective amount of a pharmaceutical composition containin g a substance which scavenges free radicals, e.g. a pyrimido-pyrimidine select ed from Dipyridamole, Mopidamol and the pharmaceutically acceptable salts thereof, and the use such substance for the manufacture of a corresponding pharmaceutical composition, optionally in combination with an agent capable of increasing NO production, more particularly HMG-CoA reductase inhibitors suc h as aspirin.
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