发明名称 PYRIMIDIN-4-ONE COMPOUNDS, PROCESS FOR THEIR PREPARATION AND PHARMACEUTICAL COMPOSITIONS CONTAINING THEM
摘要 Compound of formula (I): wherein: R1, R2, R3 and R4, which may be the same or different, each represent a hydrogen atom, a halogen atom or a group selected from alkyl, alkoxy, polyhaloalkyl, hydroxy, cyano, nitro and amino, or R1 with R2, R2 with R3, or R3 with R4, together with the carbon atoms carrying them, form an optionally substituted benzene ring or an optionally substituted heteroaromatic ring, X represents an oxygen atom or a methylene group, A represents an alkylene chain, represents an optionally substituted, unsaturated, nitrogen-containing heterocycle and R5 represents an alkyl group, its enantiomers and diastereoisomers, and addition salts thereof with a pharmaceutically acceptable acid. a medicinal products containing the same are useful as a double alpha2/5-HT2c antagonist.
申请公布号 EA200200379(A2) 申请公布日期 2002.10.31
申请号 EA20020000379 申请日期 2002.04.17
申请人 发明人
分类号 A61K31/519;A61P1/14;A61P15/10;A61P15/12;A61P25/00;A61P25/14;A61P25/16;A61P25/18;A61P25/20;A61P25/22;A61P25/24;A61P25/28;A61P43/00;C07D471/00;C07D471/04;C07D491/048;C07D491/052;C07D513/00;C07D519/00 主分类号 A61K31/519
代理机构 代理人
主权项
地址