发明名称 Menetelmä farmaseuttisesti aktiivisten 3,3-difenyylipropyyliamiinien valmistamiseksi
摘要 Novel 3,3-diphenylpropylamines of formula I <CHEM> wherein R<1> signifies hydrogen or methyl, R<2>, R<3> and R<4> independently signify hydrogen, methyl, methoxy, hydroxy, carbamoyl, sulphanoyl or halogen, and X represents a tertiary amino group -NR<5>,R<6>, wherein R<5> and R<6> signify non-aromatic hydrocarbyl groups, which may be the same or different and which together contain at least three carbon atoms, and which may form a ring together with the amine nitrogen, their salts with physiologically acceptable acids and, when the compounds can be in the form of optical isomers, the racemic mixture and the individual enantiomers, their use as drugs, especially as anticholinergic agents, their use for preparing an anticholinergic drug, pharmaceutical compositions containing the novel amines, and methods for preparing the same.
申请公布号 FI109900(B) 申请公布日期 2002.10.31
申请号 FI19900003688 申请日期 1990.07.20
申请人 PHARMACIA & UPJOHN AB, 发明人 JOENSSON,NILS AAKE;SPARF,BENGT AAKE;MIKIVER,LEMBIT;MOSES,PINCHAS;NILVEBRANT,LISBET;GLAS,GUNILLA
分类号 A61K31/13;A61K31/135;A61K31/16;A61K31/185;A61K31/40;A61K31/445;A61P25/02;C07C43/23;C07C69/734;C07C213/02;C07C213/08;C07C215/54;C07C217/62;C07C217/72;C07C309/73;C07D207/06;C07D207/08;C07D211/14;C07D211/46 主分类号 A61K31/13
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