发明名称 1, 4, 5, 6-TETRAHYDROPYRAZOLO-[3, 4-C]-PYRID IN-7-ONES AS FACTOR XA INHIBITORS
摘要 <p>The present application describes 1, 4, 5, 6-tetrahydropyrazolo-[3, 4-c]-pyridin-7-ones of the following formula or pharmaceutically acceptable salt forms thereof: wherein ring Rb is 3-amido or 4-methoxy, Ra can be cyano, trifluoromethyl, or amido, and R can be a substituted phenyl, a substituted imidazolyl, or a substituted pyridine. Compounds of the present invention are useful as inhibitors of trypsin-like serine proteases, specifically factor Xa.</p>
申请公布号 WO2002085356(A1) 申请公布日期 2002.10.31
申请号 US2002012319 申请日期 2002.04.17
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