BENZIMIDAZOLONE DERIVATIVES

摘要

Benzimidazolone derivatives typified by compounds represented by the followi ng general formula [I] and so on: wherein R1 and R2 represent each hydrogen, etc.; R3a, R3b, R4 and R5 represent each hydrogen, alkyl, etc.; R6 represent s aryl, heteroaryl, etc.; the ring A represents a 5- to 8-membered aliphatic heterocycle having a nitrogen atom; and Z represents carbonyl or sulfonyl. Because of having an antagonistic effect to muscarinic acetylcholine recepto r, the above benzimidazolone derivatives are useful as remedies and/or preventives for, e.g., Parkinson's disease, drug-induced Parkinsonism, dystonia, akinesia, pancreatitis, bilestone/cholecystitis, biliary mobility function error, achalasia, pain, itch, choline urticaria, irritable bowel syndrome, vomiting, vomiturition, stagger, Meniere's disease, rolling diseas es such as space sickness, sea sickness and car sickness and urinary errors.