摘要 |
A cyclic amidine derivative represented by the formula (I) or a salt thereof: (I) wherein R<1>, R<2>, and R<3> each represents hydrogen, C1-6 alkyl, C1-6 alkyl substituted by aryl, etc.; R<4>, R<5>, and R<7> each represents hydrogen, C1-6 alkyl, etc.; z is 0 or 1; R<6> represents hydrogen, C1-6 alkyl, (C1-6 alkyl)oxycarbonyl, etc.; n is 1 or 2; Y<1> represents a single bond, -CH2-, etc.; Y<2> represents a single bond, -CO-, etc.; and Ar represents hydrogen, a group represented by the formula (II): (II) (wherein R<10> to R<14> each represents hydrogen, C1-6 alkyl, hydroxy, C1-6 alkoxy, etc., provided that R<12> may be bonded to R<11> or R<13> to form a 5- to 8-membered heterocycle), etc. |
申请人 |
EISAI CO., LTD.;SUZUKI, SHUICHI;KOTAKE, MAKOTO;MIYAMOTO, MITSUAKI;KAWAHARA, TETSUYA |
发明人 |
SUZUKI, SHUICHI;KOTAKE, MAKOTO;MIYAMOTO, MITSUAKI;KAWAHARA, TETSUYA |