发明名称 Indazole compounds, pharmaceutical compositions, and methods for mediating or inhibiting cell proliferation
摘要 Indazole compounds that modulate and/or inhibit cell proliferation, such as the activity of protein kinases are described. These compounds and pharmaceutical compositions containing them are capable of mediating, e.g., kinases-dependent diseases to modulate and/or inhibit unwanted cell proliferation. The invention is also directed to the therapeutic or prophylactic use of pharmaceutical compositions containing such compounds, and to methods of treating cancer as well as other disease states associated with unwanted angiogenesis and/or cellular proliferation, such as diabetic retinopathy, neovascular glaucoma, rheumatoid arthritis, and psoriasis, by administering effective amounts of such compounds.
申请公布号 US2002161022(A1) 申请公布日期 2002.10.31
申请号 US20010761656 申请日期 2001.01.18
申请人 发明人 REICH SIEGFRIED HEINZ;BLECKMAN TED MICHAEL;KEPHART SUSAN ELIZABETH;ROMINES WILLIAM HENRY;WALLACE MICHAEL B.
分类号 A61K31/416;A61K31/4184;A61K31/4375;A61K31/443;A61K31/4439;A61K31/454;A61K31/4709;A61K31/4725;A61K31/5377;A61P9/00;A61P35/00;A61P43/00;C07D231/56;C07D401/04;C07D401/14;C07D403/04;C07D403/14;C07D471/04;C07D521/00;(IPC1-7):A61K31/537;A61K31/496;A61K31/470;A61K31/418 主分类号 A61K31/416
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