| 摘要 |
<p>The present invention provides an agent for topical ophthalmic treatment of a human for ocular inflammatory diseases, containing a tricyclo compound as shown by the general formula (I) or its pharmaceutically acceptable salt as the active ingredient in the concentration of 0.01% - 0.1%. The present agent for topical ophthalmic treatment continuously shows superior ocular anti-inflammatory effects by topically administering it in a low dose to the eye of the human having the ocular inflammatory diseases. The present agent is effective for symptoms caused by the ocular inflammatory diseases such as itching, flare, edema, ulcer, etc. The present agent is also effective for a subject in whom conventional anti-inflammatory agents show no improving effect (e.g., steroid and cyclosporins). The present agent is also effective for a subject for whom other anti-inflammatory agents cannot be used (e.g., steroid contraindication). The present agent is very useful especially for the reason that it shows sufficient effects by topically administering it to the eye for one to four times.</p> |
