发明名称 COMPOUNDS EXHIBITING THROMBOPOIETIN RECEPTOR AGONISM
摘要 <p>Pharmaceutical compositions exhibiting thrombopoietin receptor agonism, which contain as the active ingredient compounds of the general formula (I): X<1>-Y<1>-Z<1>-W<1> prodrugs of the same, pharmaceutically acceptable salts of both, or solvates of them wherein X<1> is optionally substituted aryl, optionally substituted heteroaryl, or the like; Y<1> is -NR<A>CO-(CH2)0-2- (wherein R<A> is hydrogen or the like) or the like; Z<1> is optionally substituted phenylene or the like; and W<1> is a group of the general formula (II): (II) (wherein R<1>, R<2>, R<3> and R<4> are each independently hydrogen, optionally substituted lower alkyl, or the like; and the broken line represents the presence or absence of a bond), or the like.</p>
申请公布号 EP1253142(A1) 申请公布日期 2002.10.30
申请号 EP20010901511 申请日期 2001.01.23
申请人 SHIONOGI & CO., LTD. 发明人 TAKEMOTO, HIROSHI;SHIOTA, TAKESHI;TAKAYAMA, MASAMI
分类号 A61K31/427;A61K31/426;A61K31/4439;A61K31/5377;A61P7/02;A61P43/00;C07D231/40;C07D233/88;C07D249/14;C07D277/46;C07D277/82;C07D285/16;C07D285/18;C07D333/38;C07D417/04;C07D417/14;(IPC1-7):C07D231/40 主分类号 A61K31/427
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