摘要 |
Novel compounds are provided which are inhibitors of MTP and thus are useful for lowering serum lipids and treating atherosclerosis and related diseases, and have the structureincluding pharmaceutically acceptable salts thereof or prodrug esters thereof, wherein q is 0, 1 or 2;Rx is H, alkyl, aryl or halogen;A is(1) a bond;(2) -O-; or(3)B is:and wherein L2, L1, R1, R2, R3, R3', R3a, R3b, R4, R4', R5, X, are as defined herein.
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