发明名称 |
Synthesis of 3-[4-(2-aminoethoxy)-benzoyl]-2-aryl-6-hydroxybenzo[b]thiophenes |
摘要 |
The present invention is directed to chemical processes for preparing 2-aryl-6-hydroxy-3-[4-(2-aminoethoxy)benzoyl]benzo[b]-thiophenes. The present invention is also directed to crystalline solvates and a non-solvated crystalline form of 6-hydroxy-2-(4-hydroxyphenyl)-3-[4-(2-piperidinoethoxy)benzoyl]-benzo[b]thiophene hydrochloride, as well as processes for their preparation.
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申请公布号 |
US6472531(B1) |
申请公布日期 |
2002.10.29 |
申请号 |
US19950469961 |
申请日期 |
1995.06.06 |
申请人 |
ELI LILLY AND COMPANY |
发明人 |
LABELL ELIZABETH SMITH;MCGILL JOHN MCNEILL;MILLER RANDAL SCOT |
分类号 |
C07D409/12;A61K31/38;A61K31/381;A61K31/4433;A61K31/445;A61K31/4535;A61P5/24;A61P15/18;A61P43/00;C07D333/56;C07D409/10;(IPC1-7):C07D409/12;C07D333/58 |
主分类号 |
C07D409/12 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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