| 发明名称 |
Compositions and methods to enhance cancer chemotherapy in p53 defective tumors |
| 摘要 |
Compositions which abrogate DNA damage induced cell cycle arrest thereby enhancing the cell killing activity of DNA damaging anticancer agents for use in the treatment of cancer, and in particular, p53 defective cancers are provided.
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| 申请公布号 |
US6472385(B1) |
申请公布日期 |
2002.10.29 |
| 申请号 |
US20000634684 |
申请日期 |
2000.08.08 |
| 申请人 |
TRUSTEES OF DARMOUTH COLLEGE |
发明人 |
EASTMAN ALAN;GRIBBLE GORDON W. |
| 分类号 |
A61K31/553;A61K45/06;A61P35/00;C07D487/22;(IPC1-7):C07D498/18;A61K3/533 |
主分类号 |
A61K31/553 |
| 代理机构 |
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代理人 |
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| 主权项 |
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