Regulatory constructs comprising intron 3 of prostate specific membrane antigen gene

摘要

Regulatory constructs comprising intron 3 of the prostate specific membrane antigen gene (PSMA). An isolated nucleic acid molecule encoding the partial sequence of intron 3 of PSMA, a vector and a recombinant expression cassette are disclosed. Also disclosed is a method of directing expression of a coding sequence in a prostate cell, a bladder cell, a breast cell and a vascular endothelial cell using the said constructs. Also disclosed is a method of treatment of cancer using the said constructs.