2-aminothiazol-fused 2-aminoindans and 2-aminotetralins and their use in treating CNS and circulation disorders

摘要

2-Aminothiazol-fused 2-aminoindans and 2-aminotetralins having the general Formula 1: wherein R1 and R2, which may be identical or different, are selected from the group consisting of a hydrogen atom, alkyl or haloalkyl groups of 1 to 7 carbon atoms, (alkyl)cycloalkyl groups of 3 to 7 carbon atoms, alkenyl or alkynyl groups of 3 to 6 carbon atoms, and arylalkyl having 1 to 3 carbon atoms in the alkyl moiety, whilst the aryl nucleus may be substituted; and n and m are 1 or 2, and the enantiomers and acid addition salts thereof. These compounds have an effect on the dopaminergic system of the central nervous system and/or the circulation.