| 发明名称 |
RECOMBINANT AAV VECTORS FOR GENE THERAPY OF HEMOPHILIA A |
| 摘要 |
The instant invention provides methods and materials for expressing a polypeptide with factor VIII activity comprising administering an rAAV vector encoding a truncated version of human factor VIII, containing, for example, a 90 kD heavy chain of factor VIII fused to a light chain of factor VIII.
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| 申请公布号 |
US2002155580(A1) |
申请公布日期 |
2002.10.24 |
| 申请号 |
US19980084425 |
申请日期 |
1998.05.27 |
| 申请人 |
SNYDER RICHARD;DULL THOMAS J.;MCGUINNESS RYAN;FINER MITCHELL H. |
发明人 |
SNYDER RICHARD;DULL THOMAS J.;MCGUINNESS RYAN;FINER MITCHELL H. |
| 分类号 |
C12N15/09;C07K14/755;C12N7/00;C12N7/01;C12N15/12;C12N15/864;(IPC1-7):C12N7/00 |
主分类号 |
C12N15/09 |
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