发明名称 |
DENSE/POROUS STRUCTURES FOR USE AS BONE SUBSTITUTES |
摘要 |
A combination dense/porous structure includes a porous element having an out er surface defining a shape having a bulk volume, the element includes a continuous framework having struts defining a plurality of interconnecting interstices throughout the bulk volume. The porous element has interconnecti ng interstices extending throughout the volume and opening through the surface. The combination dens/porous structure also includes a dense element formed from a material and having a sintered density of at least 95%, contacting at least a portion of the porous element; and an interconnection zone formed by the inter-penetration of the material forming the dense element into the porous element. The combination dense/porous structures are particularly useful as bone substitute materials and extended release delivery systems, preferable sustained release, for physiologically active agents. The interconnection zone can also be formed by a bonding phase that may or may n ot be the same material as the dense and/or porous element. A process for producing a combination dense/porous structure includes: providing a porous element; providing a dispersion comprising a ceramic or metal powder and a binder; contacting the dispersion with the porous element whereby the slip a t least partially penetrates intoat least a portion of the porous element to form an interconnection zone and a dense element formed from the dispersion and adjacent to the interconnection zone to form a dense/porous structure; treating the dense/porous structure to form a green dens/porous structure; a nd curing, drying, and/or heating the green dense/porous structure to form the combination dense/porous structure. |
申请公布号 |
CA2447683(A1) |
申请公布日期 |
2002.10.24 |
申请号 |
CA20022447683 |
申请日期 |
2002.04.16 |
申请人 |
CASSIDY, JAMES, J. |
发明人 |
CASSIDY, JAMES J.;KO, YING;NORBERG, BRIAN L.;HECKENDORF, BRADLEY R. |
分类号 |
A61F2/00;A61F2/28;A61F2/30;A61F2/42;A61F2/44;A61F2/46;A61L27/10;A61L27/56;B22F7/00;B28B1/24;B28B1/26;B28B19/00;B28B23/00;B29C45/14;C12N5/08;(IPC1-7):A61L27/10;B29C45/00;A61K9/00;A61L27/54 |
主分类号 |
A61F2/00 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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