发明名称 |
SUSPENSION OBTAINED FROM A MULTIPLE EMULSION COMPRISING A HYDROPHOBIC COMPOUND SOLID AT ROOM TEMPERATURE AND GRANULES OBTAINED BY DRYING SAID SUSPENSION |
摘要 |
The invention concerns a suspension of particles in an aqueous medium, obtainable by carrying out the following steps: (a) preparing an invert emulsion from an internal aqueous phase comprising at least an active hydrophilic substance, and an internal organic phase comprising at least a hydrophobic compound having a melting point not less than 35 DEG C, at least a non-ionic or cationic surfactant and/or at least a non-ionic or cationic amphiphilic polymer; the temperature for preparing the emulsion being not less than the melting point of the hydrophobic compound; (b) preparing the multiple emulsion by dispersing the invert emulsion in an external aqueous phase comprising at least a non-ionic polyalkoxylated surfactant and/or at least a non-ionic polyalkoxylated amphiphilic polymer and at least an anionic surfactant; the temperature for carrying out the dispersion being not less than the melting point of the hydrophobic compound; (c) bringing said resulting emulsion to a temperature not higher than the melting point of the hydrophobic compound. The invention also concerns granules obtainable by contacting said suspension with at least a drying agent. Finally, the invention further concerns the use of said suspension and said granules. |
申请公布号 |
WO02083288(A1) |
申请公布日期 |
2002.10.24 |
申请号 |
WO2002FR01271 |
申请日期 |
2002.04.11 |
申请人 |
RHODIA CHIMIE;LANNIBOIS-DREAN, HELENE;DRENO, ANNE-GAELLE |
发明人 |
LANNIBOIS-DREAN, HELENE;DRENO, ANNE-GAELLE |
分类号 |
A61K8/06;A61K8/36;A61K8/365;B01J13/00 |
主分类号 |
A61K8/06 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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