5-MEMBERED HETEROCYCLES, PREPARATION AND APPLICATION THEREOF AS MEDICAMENTS

摘要

The invention relates to thiazole, oxazole or imidazole derivatives having at least one of the following pharmacological activities:: inhibition of monoamine oxydases (MAO); inhibition of lipid peroxydation; modulation of sodium channels. The inventive compounds comprise, for example, 2,6-di tert-butyl-4-{2-[2-(methylamino)ethyl]-1,3-thiazol-4-yl}phenol; et le 2-[4-(1,1'-biphenyl-4-yl)-1 H -imidazol-2-yl]ethylcarbamate de 4-methylpentyl. By virtue of their pharmacological properties, said compounds can be used to treat one of the following disorders or diseases: Parkinson's disease, senile dementia, Alzheimer's disease, Huntington's chorea, amyotrophic lateral sclerosis, schizophrenia, depression, psychoses, migraine or pain, especially neuropathic pain.