| 发明名称 |
TROPANE ALKALOID MULTIDRUG RESISTANCE INHIBITORS FROM ERYTHROXYLUM PERVILLEI AND USE OF THE SAME |
| 摘要 |
Compounds and methods of modulating the activity of P-glycoproteins are disclosed. The method utilizes compounds derived from Erythroxylum pervillei. the compounds overcome multidrug resistance and can be used therapeutically to enhance performance of therapeutic drugs, like chemotherapeutic drug and antibiotics.
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| 申请公布号 |
WO02083669(A1) |
申请公布日期 |
2002.10.24 |
| 申请号 |
WO2002US11358 |
申请日期 |
2002.04.11 |
| 申请人 |
THE BOARD OF TRUSTEES OF THE UNIVERSITY OF ILLINOIS |
发明人 |
KINGHORN, A., DOUGLAS;PEZZUTO, JOHN, M. |
| 分类号 |
A61K31/46;A61K45/00;A61P31/04;A61P35/00;A61P43/00;C07D451/12;(IPC1-7):C07D451/12 |
主分类号 |
A61K31/46 |
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