| 发明名称 |
METHOD AND SYSTEM FOR OPTIMIZING MULTI-EPITOPE NUCLEIC ACID CONSTRUCTS AND PEPTIDES ENCODED THEREBY |
| 摘要 |
<p>The invention relates to the field of biology. In particular, the invention relates to a method and system for designing optimized multi-epitope vaccine s having selected combinations of spacer nucleic acid at the junctions of the multi-epitope constructs encoding a plurality of CTL and/or HTL eoutioe oeotudes so as to minimize the number of junciontal epitopes and provide vaccines with increased immunogenicity.</p> |
| 申请公布号 |
CA2444001(A1) |
申请公布日期 |
2002.10.24 |
| 申请号 |
CA20022444001 |
申请日期 |
2002.03.28 |
| 申请人 |
EPIMMUNE INC. |
发明人 |
BROWN, DAVID H.;NEWMAN, MARK J.;BAKER, DENISE MARIE;LIVINGSTON, BRIAN D.;CHESNUT, ROBERT;SETTE, ALESSANDRO |
| 分类号 |
C12N15/09;A61K39/00;A61K39/21;A61K39/29;A61K39/295;A61K48/00;A61P43/00;C07K14/115;C07K14/16;C12N15/86;G06F17/50;G06F19/16;G06F19/18;G06F19/22;G06F19/24;(IPC1-7):C12N15/11;G06F19/00;C07H21/00;G06F17/30;A61K31/708;G06F17/00 |
主分类号 |
C12N15/09 |
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